This Chronic Fatigue Syndrome chart presents CFS/ME as a multi-system regulatory condition rather than a single-symptom diagnosis. The layout is organised into three clear domains — Diagnostic Check, Symptom Clusters and Risk Factor Categories — guiding practitioners from core criteria to systemic expression in one coherent visual flow.
The Diagnostic Check outlines the required criteria: persistent fatigue lasting more than six months, post-exertional malaise (PEM), unrefreshing sleep, cognitive dysfunction (“brain fog”) and orthostatic intolerance — reflecting recognised evaluation standards.
Symptoms are grouped by physiological system to highlight the condition’s multi-systemic nature. Neurological and cognitive changes, exertion intolerance, immune and inflammatory features, autonomic dysfunction (including POTS patterns), neuroendocrine disruption, gastrointestinal disturbance and pain syndromes are presented as interconnected clusters rather than isolated complaints. Risk Factor Categories include infections (EBV, COVID-19, Lyme), genetic predisposition, stress or trauma, immune dysregulation, hormonal imbalance, neuroinflammation and comorbid conditions — supporting structured clinical discussion without implying direct causation.
The integrated anatomical illustration reinforces whole-body involvement while maintaining visual clarity. This is not a symptom list, but a structured systems overview designed to support recognition, explanation and informed dialogue in clinical settings.
Free customisation with your clinic’s name.
For this artwork we offer to add your clinic’s name (or website address) for free! The name will go instead of the current sub-headline on the artwork; view an illustration of this in the image gallery.
View this chart here on YouTube.
Black Edition.
This anatomy chart is available to order in a special black edition, which can be previewed in the image gallery.
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🇮🇹 Vedi i dettagli della versione italiana.
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🇩🇪 Details zur deutschen Version anzeigen.
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🇸🇪 Se fler detaljer om den svenska versionen.
🇳🇴 Se flere detaljer om den norske versjonen.
🇩🇰 Se flere detaljer af den danske version.
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